Molegro Virtual Docker is an integrated platform for predicting protein – ligand interactions. Molegro Virtual Docker handles all aspects of the docking process from preparation of the molecules to determination of the potential binding sites of the target protein, and prediction of the binding modes of the ligands. Molegro Virtual Docker offers high-quality docking based on a novel optimization technique combined with a user interface experience focusing on usability and productivity.

The Molegro Virtual Docker (MVD) has been shown to yield higher docking accuracy than other state-of-the-art docking products (MVD: 87%, Glide: 82%, Surflex: 75%, FlexX: 58%).

Molegro Virtual Docker provides:
High docking accuracy: the docking engine has been proven to correctly identify binding modes with high accuracy. Molegro Virtual Docker has been shown to outperform other docking programs with regard to identification of correct binding modes (see the technology pages for more information).
Easy-to-use interface: the built-in wizards enable the user to easily setup and perform docking runs. Advanced visualization and analysis tools are provided to examine ligand-receptor interactions and fine-tune found docking solutions.
Cross-platform: supported on Linux, Windows and Mac, allowing easy interoperabilit y between platforms.

LeaderTask is a business organizer for a modern person. LeaderTask has a smart system for managing projects, tasks, contacts, events. Want to complete more? Get tired less Earn more And permanently improve the quality of life, work hard less and contemplate peacefully more? LeaderTask will help you with that! LeaderTask = Scheduler Personal Information Manager Calendar Address Book Organizer! Forget the traditional task organizers.

They are good if you live to work. They are great if you just want to plan things and be reminded. Have a life! Try the new generation organizer that helps you plan your work so efficiently that you have more free time than ever!

CyberLink MediaShow Espresso video conversion software facilitates fast video conversion to other formats for optimal display on popular media playback devices such as iPod, PSP and Xbox or even for upload to YouTube. This video conversion software has been optimized for Intel Core i7, NVIDIA CUDA and ATI Stream. Perfect for converting many files at once, MediaShow Espresso will speedily transcode your files to the appropriate format.

TuneUp Utilities can make your Windows operating system faster, more comfortable and more secure with just a few mouse clicks. And all operations performed on the operating system are completely safe, because all changes are monitored by TuneUp Rescue Center and can be undone at any time. All TuneUp Utilities modules can be accessed through a common interface that is divided into six categories.

The software helps both beginners and experts to make Windows meet their needs in a way that is better, easier and safer. All important system options are explained in an easy way and can be turned on or off at the click of your mouse. TuneUp Utilities will then make the necessary changes in the registry or boot files automatically. We place a high value on system stability, so that Windows won’t stop working reliably. And most changes that you make can be undone in TuneUp Rescue Center – easily and safely.

TuneUp Utilities automatically runs important maintenance tasks for you, makes you aware of any problems and offers simple solutions. This ensures performance is always at its best. A slow and untidy computer is now a thing of the past for you. You can also use TuneUp Utilities to customize the appearance of your Windows system – to make working on your computer more enjoyable.

With TuneUp Utilities you will quickly make your Windows system faster and more convenient to use- and ensure that it stays like this for the long term. This makes TuneUp Utilities the perfect program for everyone: for those who would rather leave the computer maintenance to a reliable partner as well as for those who would rather do everything themselves.

The TuneUp Turbo Mode provides an immediate performance boost whenever you need it. When you use your computer in the TuneUp Turbo Mode, an analysis is performed to see which tasks, programs and functions are currently running in the background that are not strictly necessary. These programs are stopped or slowed down, allowing the additional processing power gained to be used exclusively by the programs you are actually running.

Maintain System
Regular maintenance increases the stability of your PC, but is complicated and takes a lot of time when doing it manually. Spare yourself the stress! With TuneUp Utilities, you can clean up your computer and delete unnecessary files with only one click. Neat!
1-Click Maintenance and Automatic Maintenance
Optimize system startup and shutdown
Defragment hard disks
Remove broken shortcuts
Defragment registry
Clean registry

Increase performance
Whether you are working or gaming: TuneUp Utilities increases the performance of your PC. Programs that are used rarely or never are tracked down, startup processes are shortened and unwanted garbage files are eliminated. For trouble-free working on your PC.
Turbo Mode
Configure Live Optimization
Free up disk space
Configure system startup
Display and uninstall programs

Fix problems
With only a few clicks, you can fix typical Windows problems as easy as pie – without being a PC expert yourself. TuneUp Utilities finds errors on data carriers and fixes them automatically – about 60 of the most frequent problems under XPT, VistaT, and Windows 7T. TuneUp Utilities can even restore files deleted by accident – quickly, easily, and reliably.
Fix typical problems
Restore deleted data
Check hard drive for errors
Manage running programs

Customize Windows
Give your Windows a new look with TuneUp Utilities and customize programs and system settings to meet your needs: cool new boot screens, icons, and animations provide that personalized look for your Desktop. You can easily customize the appearance of Windows and settings of many programs to your liking.
Personalize Windows appearance
Change Windows settings

Additional functions
TuneUp Utilities offers you transparency and safety and keeps you up to date. Stay informed with the System information and Optimization Report, undo changes made accidentally, or check for available updates. From fast and safe editing of the registry to deleting data – even computer experts will find applications to meet their needs.You can find all the features that provide you with an overview of your PC and more security in this area.
Display TuneUp Optimization Report
Undo changes
Check for updates
Show system information
Permanently erase data
Editing the registry

Ashampoo WinOptimizer is designed to enable both novice and advanced users to cleanse and optimize their Windows system and adapt it to their own needs. Easy-to-use menus present the individual modules of Ashampoo WinOptimizer and make it possible to measure system performance, deactivate annoying autostart entries, or delete unnecessary files, all with a mouse click. It has powerful, efficient and safe for maximum performance.

New features:
Hard Disk Defragmenter: Keeps your hard disks at maximum efficiency all the time. Now better than ever with top Vista performance.
Manual and automatic defrag options
Completely new Advanced Defrag algorithm
New Boot Time defrag makes Windows start faster
Powerful, efficient and safe for maximum performance
Exceptionally efficient, very low system load and memory use
Preview of current hard disk fragmentation with analysis

Ashampoo Uninstaller 4 completely eliminates this problem. It lets you test software with confidence because you can be sure that no trace of programs you remove are left anywhere on your system. It does this by comparing compact Before and After snapshots that identify exactly where all program components and settings are located.

Uninstalling is completely safe, with automatic backups and a special Reinstaller for quickly reinstalling programs with all their settings.

New and improved in this version
Ashampoo UnInstaller 4 is now better than ever before, with new features, improved functionality, two new utility modules and a new graphical user interface.
Improved UnInstaller
New Undeleter and File Wiper
Improved Hard Disk Defragmenter
Improved Internet Cleaner
New graphical user interface

System Mechanic keeps your PC running faster, cleaner and error-free. Its powerful arsenal of 40+ award-winning precision tools fixes stubborn errors, cleans out clutter, optimizes internet and download speeds, ensures personal security and maintains maximum computer performance automatically.

Over 98% of PC problems are caused by clutter and faulty settings that are the result of everyday PC use. System Mechanic automatically repairs errors and fragmentation, cleans out clutter, and tunes up your PC – so that it runs smoothly, reliably, and up to 300% faster! Don’t waste money on expensive “experts” to fix your PC when System Mechanic will repair, tune, and maintain it for you! Enjoy that new PC feeling again. Clear out clutter and errors for improved speed and reliability. Optimize your PC to play the latest high-performance games at maximum speeds. Accelerate download and web surfing speeds up to 300%.

System Mechanic 9 – Boost your computer’s performance and stability with advanced PC tune-up. System Mechanic gives you over 40 automatic tools to clean hard drive clutter, repair your registry, defragment drives and memory, and optimize system and internet settings.

System Mechanic Professional 9 – includes five award-winning products to give you the essential combination of internet security and PC optimization in one package: everything you need to keep your PC safe, fast, and error-free. Fix problems, boost performance, eliminate crashes, defend against spyware, viruses, and hacker threats, and much more. Use one centralized system dashboard to automatically perform all vital PC maintenance.

Cleans, defrags, and repairs registry
Accelerates PC startup 19 ways
Defrags and recovers orphaned RAM
Boosts internet speed
Complete low-level drive defrag
Turns off unused background programs

Advanced PC Tune-Up plus:
Certified virus protection
Internet intruder defense
Deleted Data Rescue
Secure Data Removal

iolo AntiVirus provides industry-certified protection from viruses, worms, trojans, and other threats by using an advanced real-time engine that provides continuous maximum protection. It includes fully integrated email scanning, hourly virus definition updates, and an intuitive interface that makes it easy to maintain a permanently virus-free PC.

iolo Personal Firewall blocks unwanted communication to and from PCs, keeping private information safe from hackers and identity thieves. Its proprietary IntelliDefense system eliminates security guesswork by automatically deciding which programs should connect to the internet using a program database of thousands of behavior profiles.

Search and Recover rescues accidentally deleted pictures, videos, email messages, documents, spreadsheets, system files, and any other file or folder from hard drives, CD/DVDs, music players, digital cameras, memory cards, and virtually all other portable digital devices.

DriveScrubber securely erases sensitive data to prevent it from falling into the wrong hands when selling, donating, recycling, or reassigning a computer. DriveScrubber overwrites and removes information permanently, using strict government and military standards to provide protection from even the most sophisticated forensic recovery methods.

System Mechanic 9 Professional Features:
Optimize your PC for peak performance
Repair problems and errors, and prevent them from re-occurring
Clean up system clutter
Remove spyware and fix security vulnerabilities
Maintain reliability and speed
iolo AntiVirus – protect against viruses, worms, trojans, and other threats
iolo Personal Firewall – protect against hackers, Internet intruders, and other unwanted communication
Search and Recover – recover deleted files, photos, email, and more from any drive or media
DriveScrubber – securely erase data from your hard drive

What’s new in version 9:
SMARTER
Tune-up Definitions . Diagnose and resolve 1000′s of new problems
FASTER
EnergyBooster . Turn off unused programs for max performance
DEEPER
Registry Tuner. Detect and fix up to 500% more registry problems
PLUS…
hundreds more enhancements that make System Mechanic more effective than ever before!

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Norton Internet Security 2010 – Strong on protection, light on system resources, award winning! Norton Internet Security runs quietly in the background to detect and block today’s complex threats and to protect your identity when you buy, bank, or browse online. The friendly and efficient product design helps minimize confusing security alerts and system slowdowns that can get in the way of your online experience.

Norton Internet Security provides essential protection from viruses, hackers, spyware, spam and other privacy threats. A comprehensive set of security tools, Norton Internet Security helps keep you safe online as you surf and email, swap files, download programs, and chat. In addition to protecting against viruses and unwelcome intrusions from the Internet.
NIS also allows you to automatically block annoying banner ads and pop-up windows, set up parental site blocking options for restricting access to specific Web sites, and selectively determine which, if any, Java applets and ActiveX controls should be allowed to download and execute on your computer. Enjoy the Internet with award-winning protection!

Key Technologies:
Anti Virus
Anti Rootkit
Bot Protection
Norton™ Safe Web
Smart Firewall
NEW! SONAR™ 2 Behavioral Protection
NEW! Norton System Insight
NEW! Norton Insight Network AntiSpam
NEW! Norton Download Insight
NEW! Norton Threat Insight
Spyware Protection
Identity Protection
Pulse Updates
Network Monitoring
Parental Controls
Vulnerability Protection
NEW! Professional Strength AntiSpam
NEW! Norton File Insight

Key Benefits:
NEW Delivers clear threat and performance explanations—Gives you greater insight into downloaded applications and files by telling you where they came from, if they can be trusted, and how they may impact your PC’s resources and performance.
NEW Identifies unsafe web sites right in your search results—Warns you of dangerous web sites and suspicious sellers so you can surf and shop online with confidence.
IMPROVED! Stops online identity theft, viruses, spyware, bots and more—Guards your PC, online activities, and your identity against all types of Internet threats.
IMPROVED! Stops attacks before they get on your PC—Proactively blocks hackers and prevents dangerous software from downloading to your computer when you surf the web.
Uses intelligence-driven Norton Insight Network for faster, fewer, shorter scans—Detects and eliminates dangerous software with the shortest scan times of any security product.

Norton Internet Security 2010 Features:
Intelligent Protection
IMPROVED! Norton Protection System delivers multiple layers of security that work together to provide comprehensive Internet threat protection.
NEW! Norton Safe Web identifies unsafe and dangerous web sites right in your search results.
IMPROVED! Norton IdentitySafe offers one-click log-ins and automatic form filling to prevent key loggers from stealing your information as you type.
NEW! Norton IdentitySafe On-the-Go lets you access your most up-to-date log-ins and passwords on any Norton Internet Security 2010 protected PC.
Industry-leading anti-phishing technology authenticates safe sites and protects you from visiting unsafe and fraudulent web sites.
NEW! Analyzes downloads, files and applications and tells you if they can be trusted before you install and use them.
IMPROVED! Vulnerability Protection guards security holes in your operating system, applications, browsers and browser plug-ins.
IMPROVED! Detects and gets rid of even the hardest to find Internet Explorerf and Firefox cookies.
Smart Firewall stops hackers and makes intelligent security decisions for you.
NEW! Parental Controls give you insight into your kids’ online activities so you can teach them good Internet habits and help keep them safe.
IMPROVED! Norton Bootable Recovery Tool repairs, restores and boots severely infected, unbootable PCs.
NEW! Professional-strength antispam protection uses the same technology as many large businesses to effectively block unwanted emails.

Engineered for Speed
IMPROVED!Proven fastest, lightest security suite for protection that won’t slow you down, get in your way, or swallow up system resources. More info
IMPROVED! Norton Insight scans only files at risk for fewer, shorter scans and the fastest scanning times in the industry. More info
Won’t slow you down when you download, copy, or edit files, or install applications. More info

Combats today’s rapid-fire attacks
NEW! Norton Insight Network uses Symantec’s global security network to provide real-time protection from the latest-breaking threats.
NEW! SONAR 2 (Symantec Online Network for Advanced Response) uses online intelligence and proactive monitoring to detect and stop new threats.
Norton Pulse Updates provide rapid mini updates every 5 to 15 minutes for up-to-the-minute local protection against the latest threats.
Prevents bots from taking control of your PC.
Finds and removes rootkits.
Prevents Internet worms from getting on your PC.
Tells you which application processes currently running on your PC are safe and which are at risk.
Norton Bootable Recovery Tool provides a deep level of cleaning for heavily infected PCs.

Provides info on threats, downloads and files
NEW! Norton Download Insight warns you of dangerous downloads before you install and use them.
NEW! Norton Threat Insight tells you if threats were detected, what actions the threats attempted to perform on your system, and how Norton Internet Security eliminated those threats.
NEW! Norton File Insight tells you where files and applications came from, if they’re trusted, and how they may be impacting your PC’s speed.

Helps keep your PC running at top speed
NEW! Norton System Insight helps you improve and maintain PC and application performance.
NEW! Automatic and on-demand application optimization improves application performance.
NEW! Norton System Insight gives you an overview of recent events on your PC such as installs, downloads, scans and detected threats, so you can see what events may have impacted your PC’s performance.
NEW! Norton System Insight resource usage graphs help you pinpoint what’s causing your PC to slow down.
NEW! Tells you how files and applications impact your PC’s performance.

Protection without disruption
Smart Scheduler conducts scans and other tasks only when your PC is idle.
Automatically switches to Silent Mode (no alerts, updates or scans) when watching movies or playing games in full-screen mode.
NEW! Automatically delays product updates and other tasks if you’re watching TV or burning CDs/DVDs.
NEW! Power Saver Settings help extend portable PC battery life by putting off power-intensive activities until your computer is plugged in.

Additional Features
NEW! Monthly report tells you what Norton Internet Security has done in the past month to protect you and your PC.
Free 24×7 support by phone, email, live chat or online knowledge base.**
Automatically scans emails and IMs for infections.
Maps and monitors your home wireless network so you can see everything connected to it — even unauthorized visitors like the PC next door.
Automatically downloads protection updates and new product features as they become available during your service period.
With the Norton Automated Renewal Service your yearly subscription can be automatically renewed for uninterrupted protection.

Why Choose Norton Internet Security:
IMPROVED! Stops online identity theft, viruses, spyware, bots and more – Guards your PC, online activities, and your identity against all types of Internet threats.
IMPROVED! Stops attacks before they get on your PC – Proactively blocks hackers and prevents dangerous software from downloading to your computer when you surf the web.
NEW! Delivers clear threat and performance explanations – Gives you greater insight into downloaded applications and files by telling you where they came from, if they can be trusted, and how they may impact your PC’s resources and performance.
NEW! Identifies unsafe web sites right in your search results – Warns you of dangerous web sites and suspicious sellers so you can surf and shop online with confidence.
Uses intelligence-driven Norton Insight Network for faster, fewer, shorter scans – Detects and eliminates dangerous software with the shortest scan times of any security product.

Supported Operating Systems:
Microsoft® Windows® XP with Service Pack 2 or later Home/Professional/Media Center
Microsoft Windows Vista (32-bit and 64-bit) Starter/Home Basic/Home Premium/Business/Ultimate
Microsoft Windows 7 (32-bit and 64-bit) Starter/Home Basic/Home Premium/Professional/Ultimate

Advanced Registry Doctor (ARD) cures your registry and thus provide a better performance of your Windows OS.Lots of programs, including MS Windows itself, have a bad habit to alter the registry in such a way, which causes appearance of different problems.

ARD finds problems of such kind and allows you to fix them either manually or automatically. Automatic repair of problems is very handy to use since it can be applied to set of problems and categories (category is a set of problems of a single kind). ARD can even find and repair invalid shortcuts, which reference to invalid file or hold invalid link to an icon.

ARD can bring some of the dead links back to life. For example, that is if you’ve accidentally moved your files (font files, help files, shared folders, shared DLLs, etc) to some other place. The main point of using ARD is that it will do the entire job for you; you just have to select which problems to search (categories) and HDD list, which will be used by the program for finding solutions. Usually you’ll have to use ARD when new program is installed/removed.

Here are some key features of “Advanced Registry Doctor Pro”:

Prevent Your Computer from Windows crashes
Make Your Computer Fast and stable in Minutes
Increase Your Computer Speed by up to 100%!
Find & Repair Problems in the Following Sections
Application Paths
Uninstall Information
COM/ActiveX (Registered version only)
Help Files
File Extensions
Font Files
Most Recently Used Files List
Shared DLLs (Registered version only)
Shared Folders
Startup Programs
Windows/MS-DOS Shortcuts
Virtual Device Drivers
Automatic Repair
Undo support
History logging
Saving of problems list
Startup Wizard
Registry Defragmentation (Professional version only)
Registry Backup/Restore (Professional version only)
System Backup (Professional version only)
Registry Defragmentation Scheduler (Professional version only)

Music, photos, and video YOUR way – all from a single software program! Connect your PC to your home entertainment hardware and control it all with a remote! Load your music on your iPod while you watch TV! All with one easy-to-use program – MEDIA CENTER! J.River Media Center has a streamlined user interface designed to make it even easier to organize, find and play your digital files, and to connect to hardware devices.

All-in-one media management app turns any Windows PC into an entertainment hub for complete control of your digital media. It connects PC to stereo, TV, remote control devices, digital cameras, scanners, and portable MP3 players. It plays all media, rips, burns, and organizes all your music, images, and video. J.River Media Center encodes and plays all popular media formats. Powerful utilities include Media Server for streaming music and images to remote PCs.

New features in J. River Media Center 14.0:
Audio
Native support of DirectShow DSP filters
Audiophile — WASAPI exclusive output using high-end USB DACs
Audiophile — Added ability to play files from memory instead of disk
Audiophile — Support for high end USB DAC’s with WASAPI
Headphone DSP makes listening more natural and comfortable.
SoundcardSwitch command for the launcher (MC14.exe), allows soundcard selection on Vista and W7
3D album view adjusts text size to display more tracks when necessary
3D album view allows playing, adding, shuffling, and adding as next to play
Improved tagging and tag compatibility

Images
Image Preview allows zoom from a thumbnail to rotate, delete, compare, edit, and more
Image thumbnail frames (optional)
Photoshop PSD file support
Single command copy / send to an editor like Photoshop, and stack new image with original

Video
Video tagging using sidecar files
Chapter Support for MKV and MP4
Chapters added to On Screen Display
Info Panel displays metadata

Television
Added new “watched” column to metadata
EPG can automatically retrieve XMLTV data
Automatic correlation of XML channel names and MC channel names
Info Panel displays metadata, including TV program art
TV program art from YADB

Theater View
Watch Hulu and YouTube from Theater View
Customizable nested views in Theater View
Customizable File Info panel to display metadata
Speed and quality enhancements
Custom backgrounds
Touch screen support
On screen clock
Remotes and Servers
Wiki articles: Remotes and Servers
Remote Relay using IR transceivers for controlling a set top box or receiver
Remote Setup Wizard
Media Center Remote learning and blasting
Media Center can connect to another Media Center to act as a remote (TRemote)
New HID remote control plug-in — supports shortcuts with keyboard, mouse, & gamepad
Remote control with REST based Web Service Interface in Library Server
Library Server supports read and write to allow for shared, multi-user database access
DLNA added to the UPnP Server
Library Server clients can write changes back to server
Library Server connections allow playback on server as Playing Now zones

Optimization
Faster file import on multi-core systems
Faster drawing on multi-core systems
Faster image rendering
Faster MP3 ID3v2 tag reading

General
New import wizard finds and suggests folders to import
Animated scrolling in lists and trees
Improved search box suggestion
New Media Center 14 Service runs when the player is running to allow talking to hardware (for remotes, portable devices, etc.) when UAC is enabled.

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